Study #1
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- Science Inside: Rao A, Clayton P, Briskey D. The effect of an orally‐dosed Gynostemma pentaphyllum extract (ActivAMP®) on body composition in overweight, adult men and women: a double‐blind, randomised, placebo‐controlled study. J Hum Nutr Diet. 2022;35:583–589. 10.1111/jhn.12936
- Study Design: Randomized, double-blind, placebo-controlled trial
- Subjects: 117 overweight men and women
- Intervention: 225mg of ActivAMP twice daily (450mg/day)
- Study Duration: 16 weeks
- Reduction in body weight
- Reduction in Body Mass Index
- Reduction in Total Fat Mass
- Reduction in Visceral Fat for Men
- Reduction in Gynoid Fat for Women
- Reduction in the Levels of TNF-Alpha, a biomarker for inflammation
Study #2
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- Science Inside: Ahn, Yejin, et al. “Effects of gypenoside L-containing Gynostemma pentaphyllum extract on fatigue and physical performance: A double-blind, placebo-controlled, randomized trial.” (2023)
- Study Design: Randomized, double-blind, placebo-controlled trial
- Subjects: 98 healthy adult men and women
- Intervention: 450mg of ActivAMP daily (450mg/day)
- Study Duration: 12 weeks
When compared to placebo, there was significant improvement in:
- VO2 max (maximal oxygen consumption during exercise)
- 1.10 ml/kg/min (p=0.001)
- Trend towards for significance* for:
- O2 pulse (oxygen consumes per heartbeat)
- Market related to endothelial function
Study #3
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- Science Inside: Nayyar D, Yan X, Xu G, et al. Gynostemma Pentaphyllum Increases Exercise Performance and Alters Mitochondrial Respiration and AMPK in Healthy Males. Nutrients. 2023;15(22):4721. Published 2023 Nov 8. doi:10.3390/nu15224721
- Study Result: When compared to placebo, there was significant improvement in:
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improved exercise performance in healthy untrained males
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improved mitochondrial respiration
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Leptin levels and blood glucose
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AMPK activation in the muscles
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Key markers related to how the body burns fat
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